Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep856 | Reproductive and Developmental Endocrinology | ECE2020

Effects of perinatal exposure to 4-tert-octylphenol (OP) on brain development and behavior in mice

Nam Tran Dinh , Myeong Go Seon , Yi Donglin , Thi Bich Thuy Vo , Jung EuiMan , Jeung Eui-Bae

Perinatal action of estrogens or aromatizable steroids at the central nervous system level is responsible for brain development. 4-tert-octylphenol (OP) is knows as an endocrine disrupting chemical (EDC) that is widespread estrogenic chemical used in the costumer produces. Thus, we hypothesis that through early contact with the central nervous system, OP could alter the processes affecting behavior. In this study, primary cortical neurons were exposure to OP (10–6</...